Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is the process of genetic examination of embryos before they are placed in the mother's uterus. PGT helps diagnose specific genetic diseases such as Cystic Fibrosis, Fragile X, Myotonic Dystrophy, Thalassemia, Tay Sachs. Reduces the likelihood of couples with certain genetic risk factors having children with the same genetic disease. 

This can be done on day 3 or 5 in the development of embryos. On day 3, embryos are taken with 1 or 2 cells biopsy taken at 7-8 cell stage. Genetic analysis helps to transfer the healthy embryo to the mother. PGD is performed in cases with recurrent miscarriages as well as advanced maternal age, in couples with recurrent unsuccessful in vitro fertilization, in cases of severe male infertility, in cases at risk of genetic disease. Advantages of detecting chromosomal abnormalities by PGT; the embryo is attached to the uterus and increases the chance of pregnancy, decreases the risk of miscarriage, and increases the chance of having a normal chromosomal baby.  

5th Day Blastocyst Embryo Biopsy (Trophectoderm Biopsy)

It is applied to blastocyst stage embryos on the 5th or 6th days of embryo development. In order for the procedure to be performed, the trophectoderm cells must protrude out of the membrane of the embryo. For this purpose, an opening is created by making laser shots on the membrane. By entering this opening, 5-6 cells are taken without damaging the internal cell mass (ICM) and the process is completed. Following the procedure, the collected cells are sent to the genetic laboratory for evaluation. The embryo is stored frozen.  

GOP IVF Center aims to make use of all kinds of science and technology in order for every patient to have a healthy baby. Studies generally show that there is a possibility of chromosomal defects in embryos. 

Preimplantation Genetic Diagnosis (PGD) | Gop IVF Center

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